Walker Carcinoma 256
نویسندگان
چکیده
Progressive growth of the Walker carcinoma @56 produces a caloric deficit in young adult, male, albino rats. The excessive expenditure of calories is not due solely to decreased food intake, for tumor-bearing rats lose more calories than do pair-fed noncancerous rats of the same age, sex, and initial weight. This result was anticipated by a previous report that rats in which the Walker tumor grew progressively lost more total lipid than did pair-fed control rats of the same age, weight, and sex (3). It seemed advisable, however, to determine the over-all caloric deficit acquired during the growth of this neoplasm.
منابع مشابه
Catabolism of xanthine and uracil in tumor-bearing rats.
The urinary excretion of allantoin and uric acid was greatly increased in rats bear ing Walker carcinoma 256. The increase was greater with more advanced tumor growth. A similar increase was also observed in the allantoin concentration of the plasma and liver of these rats. An increase in the RNA and DNA content and a decrease in the RNA/DNA ratio were found in the muscle of the tumor-bearing a...
متن کاملThe Growth and Spread of Walker 256 Carcinoma in Pinealectomized Rats.
Walker 256 carcinoma was injected into the thighs of control, sham-pinealectomized, and pinealectomized Sprague-Dawley rats weighing between 40 and 50 grams. The pinealectomized group had statistically significant shorter survival times, larger tumor diameters, and more extensive metastases than the control and sham-pinealectomized groups. Pineal cells of rats that had died of tumor had more ve...
متن کاملWalker Carcinoma 256*t
Dieta.—Male Wistar rats were placed on a semi synthetic diet at weaning, and the food consump tion of each was measured. A week later each rat was paired with one of equal body weight and food consumption. At this time one rat of each pair was designated as the experimental rat which would receive a tumor transplant; the other rat, his pair fed control, consumed the amount of diet eaten by th...
متن کاملAn experimental study of necrosis in tumors.
Factors that regulate the amount of viable tumor an animal can support have been studied in rats bearing Walker carcinoma 256. There is a maximum amount of viabletumor an animal can support, but continued growth of tumor resulting in increase in the amount of necrotic tumor occurs until death of a rat bearing Walker carcinoma 256. The number and location of tumors in an animal do not significan...
متن کاملSerum Mucoid Levels in Rats Bearing Walker Carcinoma 256 and the Effect of Surgical Extirpation of the Malignancy.
In rats given implants of Walker 256 tumor a sizable increase in tumor mass has been shown to precede significant increases in the serum mucoid levels. Surgical extirpa tion of the tumor leads to a return of the serum mucoids to normal values. If sub stantial metastasis has occurred, the serum mucoid values do not return to normal. If minimal amounts of tumor remain in situ or in unsuspected me...
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